CHROMOSOMAL AND TEMPERATURE-DEPENDENT SEX DETERMINATION - THE SEARCH FOR A CONSERVED MECHANISM

被引：17

作者：

CORIAT, AM

VALLELEY, E

FERGUSON, MWJ

SHARPE, PT

机构：

[1] UNITED MED & DENT SCH, GUYS HOSP, DEPT CRANIOFACILA DEV, LONDON SE1 9RT, ENGLAND

[2] UNIV MANCHESTER, SCH BIOL SCI, DEPT CELL & STRUCT BIOL, MANCHESTER M13 9PT, ENGLAND

来源：

JOURNAL OF EXPERIMENTAL ZOOLOGY | 1994年 / 270卷 / 01期

基金：

英国惠康基金;

关键词：

D O I：

10.1002/jez.1402700112

中图分类号：

Q95 [动物学];

学科分类号：

071002 ;

摘要：

To test the hypothesis that the same (or similar) genes may be involved in chromosomal sex determination and temperature dependent sex determination we investigated the expression of the mammalian testis determining gene SRY in the American alligator (Alligator mississippiensis), a species with temperature dependent sex. We have cloned Alligator SRY-related genes (A-Srys) which constitute three major gene classes with high degrees of sequence homology (45-87%) to mammalian SRY and related genes. Expression analysis and cellular localisation studies using staged embryonic material from male and female incubation temperatures are underway to assess the role of A-Sry genes in temperature dependent sex determination. (C) 1994 Wiley-Liss, Inc.

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页码：112 / 116

页数：5

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