TELOMERE SHORTENING IN CHRONIC LIVER-DISEASES

被引:132
作者
KITADA, T [1 ]
SEKI, S [1 ]
KAWAKITA, N [1 ]
KUROKI, T [1 ]
MONNA, T [1 ]
机构
[1] OSAKA CITY UNIV,SCH MED,DEPT INTERNAL MED 3,OSAKA 545,JAPAN
关键词
D O I
10.1006/bbrc.1995.1774
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
We measured the telomere length in patients with chronic hepatitis or liver cirrhosis and found a significant telomere shortening in the liver with chronic liver disease compared to that in the normal liver. The telomere length tended to decrease with the progression of chronic liver disease. (C) 1995 Academic Press, Inc.
引用
收藏
页码:33 / 39
页数:7
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