CHROMATOGRAPHIC STUDIES OF THE ENANTIOMERIC COMPOSITION OF SOME THERAPEUTIC COMPOSITIONS APPLIED IN THE TREATMENT OF LIVER AND KIDNEY-DISEASES

被引：24

作者：

SYBILSKA, D ^{[1
]}

KOWALCZYK, J ^{[1
]}

ASZTEMBORSKA, M ^{[1
]}

OCHOCKA, RJ ^{[1
]}

LAMPARCZYK, H ^{[1
]}

机构：

[1] MED ACAD GDANSK,FAC PHARM,PL-80416 GDANSK,POLAND

来源：

JOURNAL OF CHROMATOGRAPHY A | 1994年 / 665卷 / 01期

关键词：

D O I：

10.1016/0021-9673(94)87033-0

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A gas-liquid chromatographic system with alpha-cyclodextrin in formamide medium (coated on Chromosorb) was used for the separation of enantiomers of alpha-pinene, beta-pinene, limonene and camphene in medicines applied in the therapy of liver and kidney diseases. The drugs under investigation were produced in Poland (Terpichol and Terpinex), in Germany (Rowachol and Rowatinex) and in Slovenia (Uroterp). It was found that, depending on the manufacturer, medicines possessing similar chemical compositions differ considerably from one another regarding the content of enantiomers, mainly those of alpha-pinene.

引用

页码：67 / 73

页数：7

共 19 条

[11] INHIBITION OF HEPATIC S-3-HYDROXY-3-METHYLGLUTARYL-COA REDUCTASE AND INVIVO RATES OF LIPOGENESIS BY A MIXTURE OF PURE CYCLIC MONOTERPENES [J].