EVALUATION OF METHODS FOR THE SEPARATION OF TRIMETHYLSELENONIUM ION AS A MAJOR, MINOR OR GENERAL METABOLITE USING NEUTRON-ACTIVATION ANALYSIS

被引：5

作者：

BLOTCKY, AJ ^{[1
]}

CLAASSEN, JP ^{[1
]}

RACK, EP ^{[1
]}

SHOOP, DM ^{[1
]}

机构：

[1] DEPT VET AFFAIRS MED CTR, OMAHA, NE 68105 USA

来源：

JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY-ARTICLES | 1994年 / 181卷 / 02期

关键词：

D O I：

10.1007/BF02037645

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Trinethylselenonium (TMSe) ion was separated by dual-column ion-exchange chromatography and assayed by neutron activation analysis. The TMSe content of the selenium in human urine was found to be (14 +/- 2)%, consistent with literature values. An altemate, published, multi-step procedure employing Reineckate precipitation followed by decomposition/volatilization conversion of selenium into dimethylselenide, perchloric acid digestion into selenite and subsequent analysis employing inductively coupled plasma mass spectrometry (ICP-MS) was evaluated. A maximum recovery of TMSe was estimated at 32%. It has been suggested that losses in each step of a multi step procedure yield low recoveries as reported in the literature.

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页码：395 / 400

页数：6

相关论文

共 18 条

[1] DETERMINATION OF HUMAN AND SPRAGUE-DAWLEY RAT TRIMETHYLSELENONIUM ION AND TOTAL SELENIUM URINE CONCENTRATIONS FROM ENDOGENOUS BODY SELENIUM POOL BY NEUTRON-ACTIVATION ANALYSIS [J].

BLOTCKY, AJ ;

CLAASSEN, JP ;

RACK, EP .

JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY-ARTICLES, 1992, 161 (01) :11-20

[2] DETERMINATION OF TRIMETHYLSELENONIUM ION IN URINE BY ION-EXCHANGE CHROMATOGRAPHY AND MOLECULAR NEUTRON-ACTIVATION ANALYSIS [J].

BLOTCKY, AJ ;

HANSEN, GT ;

OPELANIOBUENCAMINO, LR ;

RACK, EP .

ANALYTICAL CHEMISTRY, 1985, 57 (09) :1937-1941

[3] DETERMINATION OF SELENIUM METABOLITES IN BIOLOGICAL-FLUIDS USING INSTRUMENTAL AND MOLECULAR NEUTRON-ACTIVATION ANALYSIS [J].

BLOTCKY, AJ ;

EBRAHIM, A ;

RACK, EP .

ANALYTICAL CHEMISTRY, 1988, 60 (24) :2734-2737

[4] SIMULTANEOUS DETERMINATION OF SELENITE AND TRIMETHYLSELENONIUM IONS IN URINE BY ANION-EXCHANGE CHROMATOGRAPHY AND MOLECULAR NEUTRON-ACTIVATION ANALYSIS [J].

BLOTCKY, AJ ;

HANSEN, GT ;

BORKAR, N ;

EBRAHIM, A ;

RACK, EP .

ANALYTICAL CHEMISTRY, 1987, 59 (17) :2063-2066

[5]

Burk R.F., 1976, TRACE ELEMENTS HUMAN, V2, P105

[6] TRIMETHYL SELENIDE . A URINARY METABOLITE OF SELENITE [J].

BYARD, JL .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1969, 130 (1-2) :556-&

[7] THE METABOLISM OF SELENOMETHIONINE, SE-METHYLSELENOCYSTEINE, THEIR SELENONIUM DERIVATIVES, AND TRIMETHYLSELENONIUM IN THE RAT [J].

FOSTER, SJ ;

KRAUS, RJ ;

GANTHER, HE .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1986, 251 (01) :77-86

[8] ANALYSIS OF SELENIUM METABOLITES IN URINE SAMPLES OF MINKE WHALE (BALAENOPTERA-ACUTOROSTRATA) USING ION-EXCHANGE CHROMATOGRAPHY [J].

HASUNUMA, R ;

OGAWA, T ;

FUJISE, Y ;

KAWANISHI, Y .

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY, 1993, 104 (01) :87-89

[9]

HASUNUMA R, 1993, B ENVIRON CONTAM TOX, V50, P19, DOI 10.1007/BF00196535

[10] ANALYSIS OF TRIMETHYLSELENONIUM ION IN URINE BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].

KRAUS, RJ ;

FOSTER, SJ ;

GANTHER, HE .

ANALYTICAL BIOCHEMISTRY, 1985, 147 (02) :432-436