OCULAR AUTONOMIC NERVE FUNCTION IN LAMBERT-EATON MYASTHENIC SYNDROME

被引:24
作者
CLARK, CV [1 ]
NEWSOMDAVIS, J [1 ]
SANDERS, MD [1 ]
机构
[1] NATL HOSP,LONDON WC1N 3BG,ENGLAND
关键词
D O I
10.1038/eye.1990.61
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Autonomie innervation to the eye and ocular adnexae was assessed in seven patients with Lambert-Eaton Myasthenic Syndrome and 50 age-matched control subjects. Pupil responses to light were abnormal in 69% of LEMS patients, compared with 18% of the control group. Reflex tear production—a screening test for parasym-pathetic innervation to the lacrimal gland—was below the accepted normal limit in 69% of LEMS patients. Parasympathetic and sympathetic denervation hypersensitivity of the iris musculature were individually present in 57% of LEMS patients, compared with 6% of control subjects. The association between autonomie dysfunction and Lambert-Eaton Myasthenic Syndrome is discussed. © 1990, College of Ophthalmologists. All right reserved.
引用
收藏
页码:473 / 481
页数:9
相关论文
共 27 条
[21]   CHOLINERGIC DYSAUTONOMIA AND EATON-LAMBERT SYNDROME [J].
RUBENSTEIN, AE ;
HOROWITZ, SH ;
BENDER, AN .
NEUROLOGY, 1979, 29 (05) :720-723
[22]  
Scheie HG, 1940, ARCH OPHTHALMOL-CHIC, V24, P225
[23]   TESTING A SERVOANALYTIC HYPOTHESIS FOR PUPIL OSCILLATIONS [J].
STARK, L ;
CORNSWEET, TN .
SCIENCE, 1958, 127 (3298) :588-588
[24]   HIPPUS [J].
THOMPSON, HS ;
SULLIVAN, KN .
ARCHIVES OF INTERNAL MEDICINE, 1969, 123 (05) :598-+
[25]  
THOMPSON HS, 1971, AM J OPHTHALMOL, V17, P1116
[26]   PUPIL CYCLE TIME IN OPTIC-NERVE COMPRESSION [J].
WEINSTEIN, JM ;
VANGILDER, JC ;
THOMPSON, HS .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 1980, 89 (02) :263-267
[27]   PUPIL SIZE AND SPONTANEOUS PUPILLARY WAVES ASSOCIATED WITH ALERTNESS, DROWSINESS, AND SLEEP [J].
YOSS, RE ;
MOYER, NJ ;
HOLLENHORST, RW .
NEUROLOGY, 1970, 20 (06) :545-+