MONOCLONAL-ANTIBODY BASED CAPTURE ELISA/ELIFA FOR DETECTION OF COXIELLA-BURNETII IN CLINICAL SPECIMENS

被引：26

作者：

THIELE, D

KARO, M

KRAUSS, H

机构：

[1] Institut für Hygiene and Infektionskrankheiten der Tiere, Justus Liebig Universitä, Giessen, D-6300

来源：

EUROPEAN JOURNAL OF EPIDEMIOLOGY | 1992年 / 8卷 / 04期

关键词：

Q-FEVER; COXIELLA-BURNETII; CAPTURE ELISA; MONOCLONAL ANTIBODY;

D O I：

10.1007/BF00146378

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

A CAPTURE ELISA/ELIFA system based on monoclonal capture and biotinylated monoclonal detection antibody is described. The assay is fast, highly specific and detects a minimum dose of 2500 Coxiella (C.) burretii particles. In contrast to the sophisticated and cumbersome isolation procedures, even non-specialized laboratories could use this assay system for investigating clinical samples of different origin for C. burnetii within a short period of time.

引用

页码：568 / 574

页数：7

共 23 条

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Yeaman M.R., Mitscher L.A., Bacca O.G., In vitro susceptibility of Coxiella burnetii to antibiotics, including several quinolones, Antimicrob. Agents Chemother., 31, pp. 1079-1084, (1987)

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