EFFECT OF FENARIMOL ON STEROL BIOSYNTHESIS IN SUSPENSION CULTURES OF BRAMBLE CELLS

被引：52

作者：

SCHMITT, P

BENVENISTE, P

机构：

[1] Institut de Botanique, Laboratoire de Biochimie Végétale, E.R.A. du C.N.R.S. No. 487, 67087 Strasbourg Cedex, 28, rue Goethe

来源：

PHYTOCHEMISTRY | 1979年 / 18卷 / 10期

关键词：

14α-methyl demethylation; !sup]1[!/sup]H NMR of Δ[!sup]8[!/sup]-sterols; fenarimol; Rosaceae; Rubus fruticosus; sterol biosynthesis inhibitor;

D O I：

10.1016/0031-9422(79)80179-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Bramble suspension cultures normally contain Δ5-sterols (sitosterol, campesterol and isofucosterol). When the cells were grown in a medium supplemented with fenarimol, 14α-methyl sterols accumulated. Eight 14α-methyl sterols, including two new compounds, 4α,14α-dimethyl-stigmasta-8,Z-24(28)-dien-3β-ol and 14α-methyl-stigmasta-8,Z-24(28)-dien-3β-ol, were identified. Fenarimol probably inhibited the 14α-methyl demethylation. Cell lines growing permanently in 2 fenarimol-supplemented medium were obtained. © 1979.

引用

页码：1659 / 1665

页数：7

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