CIRCULAR FORMS OF DNA SYNTHESIZED BY ROUS-SARCOMA VIRUS INVITRO

被引：8

作者：

CLAYMAN, CH ^{[1
]}

MOSHARRAFA, ET ^{[1
]}

ANDERSON, DL ^{[1
]}

FARAS, AJ ^{[1
]}

机构：

[1] VIRGINIA POLYTECH INST & STATE UNIV,DEPT BIOL,BLACKSBURG,VA 24061

来源：

SCIENCE | 1979年 / 206卷 / 4418期

关键词：

D O I：

10.1126/science.91199

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Electron microscopic analysis of the DNA product synthesized by detergent-disrupted preparations of Rous sarcoma virus in vitro revealed the presence of several interesting molecular forms including covalently closed circular DNA. The identification of such circular DNA indicates that virions of retroviruses contain all the components necessary to facilitate the complete synthesis of mature forms of viral DNA and therefore provide a useful system to delineate the molecular mechanisms involved in their synthesis. Copyright © 1979 AAAS.

引用

页码：582 / 584

页数：3

共 25 条

[21] USE OF ALKALINE SUCROSE GRADIENTS IN A ZONAL ROTOR TO DETECT INTEGRATED AND UNINTEGRATED AVIAN-SARCOMA VIRUS-SPECIFIC DNA IN CELLS
VARMUS, HE
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[22] UNINTEGRATED VIRAL-DNA IS SYNTHESIZED IN CYTOPLASM OF AVIAN-SARCOMA VIRUS-TRANSFORMED DUCK CELLS BY VIRAL-DNA POLYMERASE
VARMUS, HE
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[23] STUDIES ON REVERSE-TRANSCRIPTASE OF RNA TUMOR-VIRUSES .3. PROPERTIES OF PURIFIED MOLONEY MURINE LEUKEMIA-VIRUS DNA-POLYMERASE AND ASSOCIATED RNASE-H
VERMA, IM
[J]. JOURNAL OF VIROLOGY, 1975, 15 (04) : 843 - 854
[24] GENOME ORGANIZATION OF RNA TUMOR-VIRUSES .1. INVITRO SYNTHESIS OF FULL-GENOME-LENGTH SINGLE-STRANDED AND DOUBLE-STRANDED VIRAL-DNA TRANSCRIPTS
VERMA, IM
[J]. JOURNAL OF VIROLOGY, 1978, 26 (03) : 615 - 629
[25] WEIS JC, UNPUBLISHED

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