SYNTHESIS AND CONFORMATION OF DIHISTAMINE DERIVATIVES OF CYCLOMALTOHEPTAOSE (BETA-CYCLODEXTRIN)

被引:20
作者
CUCINOTTA, V [1 ]
DALESSANDRO, F [1 ]
IMPELLIZZERI, G [1 ]
VECCHIO, G [1 ]
机构
[1] CNR, IST STUDIO SOSTANZE NAT INTERESSE ALIMENTARE & CHI, I-95125 CATANIA, ITALY
关键词
D O I
10.1016/0008-6215(92)84096-B
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The three isomeric dihistamine derivatives of beta-cyclodextrin (cyclomaltoheptaose) have been prepared and investigated by H-1- and C-13-n.m.r. spectroscopy. For each isomer, neither of the imidazole rings is included in the cavity, but a reciprocal influence of the histamine chains is observed, suggesting that they have an organised structure.
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页码:95 / 102
页数:8
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