MODIFICATION OF SUPPORTED LIPID-MEMBRANES BY ATOMIC FORCE MICROSCOPY

被引：28

作者：

BRANDOW, SL

TURNER, DC

RATNA, BR

GABER, BP

机构：

[1] Center for Biomolecular Science and, Engineering, Naval Research Laboratory, Washington

来源：

BIOPHYSICAL JOURNAL | 1993年 / 64卷 / 03期

关键词：

D O I：

10.1016/S0006-3495(93)81450-4

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

The atomic force microscope (AFM) was used to structurally modify supported lipid bilayers in a controlled quantitative manner. By increasing the force applied by the AFM tip, lipid was removed from the scanned area, leaving a cut through the lipid bilayer. Cuts were repaired with the AFM by scanning the region with a controlled force and driving lipid back into the cut. A slow self-annealing of cuts was also observed.

引用

页码：898 / 902

页数：5

共 22 条

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