CORRELATION OF ISOMERIC FATTY-ACIDS IN HUMAN ADIPOSE-TISSUE WITH CLINICAL RISK-FACTORS FOR CARDIOVASCULAR-DISEASE

被引：75

作者：

HUDGINS, LC ^{[1
]}

HIRSCH, J ^{[1
]}

EMKEN, EA ^{[1
]}

机构：

[1] USDA ARS,NO REG RES CTR,PEORIA,IL 61604

来源：

AMERICAN JOURNAL OF CLINICAL NUTRITION | 1991年 / 53卷 / 02期

关键词：

TRANS FATTY ACIDS; CIS FATTY ACIDS; ADIPOSE TISSUE FATTY ACIDS; HEART DISEASE; ATHEROSCLEROSIS; HYPERLIPIDEMIA; HYDROGENATED VEGETABLE OIL; HYPERTENSION; OBESITY;

D O I：

10.1093/ajcn/53.2.474

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

The relationships between the adipose tissue concentrations of 19 geometric and positional fatty acid isomers and 10 cardiovascular disease risk factors were determined in 76 free-living adult males. The percentages for trans isomers (total xBAR +/- SD 4.14 +/- 0.97%) and cis isomers (total xBAR +/- SD 2.91 +/- 0.34%) in adipose tissue generally agreed with dietary estimates based on the consumption of hydrogenated oils. A major exception was the percentage of 11c-18:1, which was twofold higher in adipose tissue. The total level of fatty acid isomers in adipose tissue or a factor (derived by factor analysis) that was representative of isomers of dietary origin was not significantly correlated with the cardiovascular risk factors. Only three trans isomers (11t-18:1, 12t-18:1, and 5t-14:1) and three cis isomers (11c-18:1, 13c-18:1, and 7c-16:1) were weakly correlated either positively or negatively with age, body mass index, plasma and lipoprotein cholesterol, and/or blood pressure (P < 0.05, r > 0.231).

引用

页码：474 / 482

页数：9

共 60 条

[1] ORIGIN OF CIS-9, TRANS-11-OCTADECADIENOIC AND TRANS-9, TRANS-11-OCTADECADIENOIC ACIDS IN THE DEPOT FAT OF PRIMATES FED A DIET RICH IN LARD AND CORN-OIL AND IMPLICATIONS FOR THE HUMAN DIET
ACKMAN, RG
EATON, CA
SIPOS, JC
CREWE, NF
[J]. CANADIAN INSTITUTE OF FOOD SCIENCE AND TECHNOLOGY JOURNAL-JOURNAL DE L INSTITUT CANADIEN DE SCIENCE ET TECHNOLOGIE ALIMENTAIRES, 1981, 14 (02): : 103 - 107
[2] SYNTHESIS OF CIS AND TRANS METHYL 8-OCTADECENOATE-D2 AND 13-OCTADECENOATE-D2 AND D4 ISOMERS
ADLOF, RO
MILLER, WR
EMKEN, EA
[J]. JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 1978, 15 : 625 - 636
[3] DISTRIBUTION OF HEXADECENOIC, OCTADECENOIC AND OCTADECADIENOIC ACID ISOMERS IN HUMAN-TISSUE LIPIDS
ADLOF, RO
EMKEN, EA
[J]. LIPIDS, 1986, 21 (09) : 543 - 547
[4] AHRENS EH, 1957, LANCET, V1, P943
[5] HYDROGENATED FATS IN DIET AND LIPIDS IN SERUM OF MAN
ANDERSON, JT
KEYS, A
GRANDE, F
[J]. JOURNAL OF NUTRITION, 1961, 75 (04) : 388 - &
[6] NUMBER OF DAYS OF FOOD-INTAKE RECORDS REQUIRED TO ESTIMATE INDIVIDUAL AND GROUP NUTRIENT INTAKES WITH DEFINED CONFIDENCE
BASIOTIS, PP
WELSH, SO
CRONIN, FJ
KELSAY, JL
MERTZ, W
[J]. JOURNAL OF NUTRITION, 1987, 117 (09) : 1638 - 1641
[7] THE RELATIONSHIP OF DIETARY-FAT TO PLASMA-LIPID LEVELS AS STUDIED BY FACTOR-ANALYSIS OF ADIPOSE-TISSUE FATTY-ACID COMPOSITION IN A FREE-LIVING POPULATION OF MIDDLE-AGED AMERICAN-MEN
BERRY, EM
HIRSCH, J
MOST, J
MCNAMARA, DJ
THORNTON, J
[J]. AMERICAN JOURNAL OF CLINICAL NUTRITION, 1986, 44 (02) : 220 - 231
[8] MATHEMATICAL RELATIONSHIP BETWEEN THE FATTY-ACID COMPOSITION OF THE DIET AND THAT OF THE ADIPOSE-TISSUE IN MAN
BEYNEN, AC
HERMUS, RJJ
HAUTVAST, JGAJ
[J]. AMERICAN JOURNAL OF CLINICAL NUTRITION, 1980, 33 (01) : 81 - 85
[9] RAPID SAMPLING AND LONG-TERM STORAGE OF SUBCUTANEOUS ADIPOSE-TISSUE BIOPSIES FOR DETERMINATION OF FATTY-ACID COMPOSITION
BEYNEN, AC
KATAN, MB
[J]. AMERICAN JOURNAL OF CLINICAL NUTRITION, 1985, 42 (02) : 317 - 322
[10] BOUSTANI S E, 1989, Metabolism Clinical and Experimental, V38, P315

← 1 2 3 4 5 6 →