THE SCLERODERMA-LIKE SYNDROME OF INSULIN-DEPENDENT DIABETES-MELLITUS

被引：28

作者：

BRIK, R

BERANT, M

VARDI, P

机构：

[1] Department of Pediatrics, Section of Rheumatology, Faculty of Medicine, Technion Israel Institute of Technology, Haifa

[2] Rambam Medical Center, Israel Institute of Technology, Faculty of Medicine, Haifa

[3] Juvenile Diabetes Clinic, Technion(Israel Institute of Technology), Faculty of Medicine, Haifa

来源：

DIABETES-METABOLISM REVIEWS | 1991年 / 7卷 / 02期

关键词：

D O I：

10.1002/dmr.5610070205

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The scleroderma-like syndrome (SLS) of diabetes consists of limited joint mobility and digital sclerosis. It is described in 8-50% of insulin-dependent diabetes mellitus patients and is the earliest clinically apparent long-term complication of diabetes in children and adolescents. The frequency of this finding appears to be related to the duration of diabetes and increasing age. Less clear are the relationships between this syndrome and glycaemic control or genetic factors. SLS is an easily identifiable marker for those young patients who may be at increased risk for the development of early microvascular complications. Recognition of this characterization will permit the clinician to focus.on newer and improved techniques for long-term physiological control of the diabetes, in an attempt to prevent microvascular disease.

引用

页码：121 / 128

页数：8

共 59 条

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