THE SCLERODERMA-LIKE SYNDROME OF INSULIN-DEPENDENT DIABETES-MELLITUS

被引：28

作者：

BRIK, R

BERANT, M

VARDI, P

机构：

[1] Department of Pediatrics, Section of Rheumatology, Faculty of Medicine, Technion Israel Institute of Technology, Haifa

[2] Rambam Medical Center, Israel Institute of Technology, Faculty of Medicine, Haifa

[3] Juvenile Diabetes Clinic, Technion(Israel Institute of Technology), Faculty of Medicine, Haifa

来源：

DIABETES-METABOLISM REVIEWS | 1991年 / 7卷 / 02期

关键词：

D O I：

10.1002/dmr.5610070205

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The scleroderma-like syndrome (SLS) of diabetes consists of limited joint mobility and digital sclerosis. It is described in 8-50% of insulin-dependent diabetes mellitus patients and is the earliest clinically apparent long-term complication of diabetes in children and adolescents. The frequency of this finding appears to be related to the duration of diabetes and increasing age. Less clear are the relationships between this syndrome and glycaemic control or genetic factors. SLS is an easily identifiable marker for those young patients who may be at increased risk for the development of early microvascular complications. Recognition of this characterization will permit the clinician to focus.on newer and improved techniques for long-term physiological control of the diabetes, in an attempt to prevent microvascular disease.

引用

页码：121 / 128

页数：8

共 59 条

[11]

Barta L, Flexion contractures in a diabetic child (Rosenbloom syndrome), Eur J Pediatr, 135, pp. 101-102, (1980)

[12]

Rosenbloom AL, Silverstein JH, Legotte DC, Richardson K, McCallum M, Limited joint mobility in childhood diabetes indicates increased risk for microvascular disease, N Engl J Med, 305, pp. 191-194, (1981)

[13]

Kennedy L, Archer DB, Campbell SL, Beacon R, Carson DJ, Johnson PB, Maguire CJ, Limited joint mobility in type I diabetes mellitus, Postgrad Med J, 58, pp. 481-484, (1982)

[14]

Lawson PM, Maneschi F, Kohner EM, The relationship of hand abnormalities to diabetes and diabetic retinopathy, Diabetes Care, 6, pp. 140-143, (1983)

[15]

Silverstein JH, Fornell R, Donnelly W, Bankes R, Stratt R, Spillar R, Rosenbloom AL, Correlates of biopsy studied nephropathy in young patients with insulin dependent diabetes mellitus, J Pediatr, 106, pp. 196-205, (1985)

[16]

Beacom R, Gillespie EL, Middleton D, Sawhney B, Kennedy L, Limited joint mobility in insulin dependent diabetes: relationship of retinopathy, peripheral nerve function and HLA status, Q J Med, 219, pp. 337-344, (1985)

[17]

Buckingham B, Perejda AJ, Sandborg C, Kershnar AK, Uitto J, Skin, joint and pulmonary changes in type I diabetes mellitus, Am J Dis Child, 140, pp. 420-423, (1986)

[18]

Starkman HS, Gleason RE, Rand LI, Miller DE, Soeldener JS, Limited joint mobility (LJM) of the hand in patients with diabetes mellitus: relation to chronic complications, Ann Rheum Dis, 45, pp. 130-135, (1986)

[19]

Brink S, Limited joint mobility as a risk factor for diabetes complications, Clin Diabetes, 5, pp. 121-127, (1987)

[20]

Seibold J, Digital sclerosis in children with insulin dependent diabetes mellitus, Arthritis Rheum, 25, pp. 1357-1361, (1982)

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