NEUROBLASTOMA IN A CHILD WITH WIEDEMANN-BECKWITH SYNDROME

被引：15

作者：

CHITAYAT, D ^{[1
]}

FRIEDMAN, JM ^{[1
]}

DIMMICK, JE ^{[1
]}

机构：

[1] UNIV BRITISH COLUMBIA,BRITISH COLUMBIA CHILDRENS HOSP,DEPT PATHOL,VANCOUVER V6T 1W5,BC,CANADA

来源：

AMERICAN JOURNAL OF MEDICAL GENETICS | 1990年 / 35卷 / 03期

关键词：

Chormosomal abnormality; Embryonal tumors; Wiedemann-Beckwith syndrome;

D O I：

10.1002/ajmg.1320350322

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

We report on a patient with Wiedemann-Beckwith syndrome (WBS) who developed abdominal neuroblastoma. Although WBS patients are known to have a higher incidence of embryonal tumors, this is only the 4th known case of neuroblastoma associated with this syndrome. Chromosomes on peripheral lymphocytes and tumor cells were normal. Children with WBS should be screened for a variety of embryonal neoplasms, not only Wilms tumor.

引用

页码：433 / 436

页数：4