INHIBITORY EFFECTS OF 3-NITRO-2,4,6-TRIHYDROXYBENZAMIDES ON EPSTEIN-BARR-VIRUS EARLY ANTIGEN INDUCTION

被引：9

作者：

HONDA, I

TOKUDA, H

KOZUKA, M

YONEYAMA, K

NISHINO, H

IWASHIMA, A

SHIBAGAKI, M

NOMA, M

TAKAHASHI, N

YOSHIDA, S

机构：

[1] KYOTO PREFECTURAL UNIV MED,DEPT BIOCHEM,KYOTO 602,JAPAN

[2] KYOTO PHARMACEUT UNIV,KYOTO 607,JAPAN

[3] UTSUNOMIYA UNIV,FAC AGR,WEED CONTROL RES INST,UTSUNOMIYA,TOCHIGI 321,JAPAN

[4] INST PHYS & CHEM RES,SAITAMA 35101,JAPAN

来源：

CANCER LETTERS | 1991年 / 59卷 / 02期

关键词：

EPSTEIN-BARR VIRUS; 3-NITRO-2,4,6-TRIHYDROXYBENZAMIDES; ANTIGEN INDUCTION;

D O I：

10.1016/0304-3835(91)90170-M

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Inhibitory effects of a series of 3-nitro-2,4,6-trihydroxybenzamides on Epstein-Barr virus early antigen (EBV-EA) induction were examined using Raji cells. Some of the tested compounds showed highly inhibitory activity, the N-octyl amide derivative being the most active among them. These results suggest the possibility that 3-nitro-2,4,6-trihydroxybensamides might be listed as novel inhibitors of tumor promotion.

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收藏

页码：83 / 88

页数：6

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