IDENTIFICATION OF INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN-2 (IGF-BP-2) AND A LOW-MOLECULAR-WEIGHT IGF-BP IN HUMAN SEMINAL PLASMA

被引：53

作者：

ROSENFELD, RG

PHAM, H

OH, Y

LAMSON, G

GIUDICE, LC

机构：

[1] STANFORD UNIV, MED CTR, DEPT PEDIAT, STANFORD, CA 94305 USA

[2] STANFORD UNIV, MED CTR, DEPT GYNECOL & OBSTET, STANFORD, CA 94305 USA

来源：

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM | 1990年 / 70卷 / 02期

关键词：

D O I：

10.1210/jcem-70-2-551

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Three distinct binding proteins for the insulin-like growth factors (IGF-BPs) have recently had their cDNAs cloned and sequenced. We have evaluated IGF-BP expression in normal, oligospermic and azospermic human seminal plasma (SP), and have identified IGF-BP-2 in all samples. Additionally, SP contains a non-glycosylated low molecular weight IGF-BP (24K), which does not appear to be structurally or immunologically related to IGF-BP-1, -2 or -3. © 1990 by The Endocrine Society.

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页码：551 / 553

页数：3

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