THE T,X,P-PHASE DIAGRAM OF BINARY PHOSPHOLIPID MIXTURES

被引：13

作者：

LANDWEHR, A ^{[1
]}

WINTER, R ^{[1
]}

机构：

[1] UNIV DORTMUND,LEHRSTUHL PHYS CHEM 1,OTTO HAHN STR 6,D-44221 DORTMUND,GERMANY

来源：

BERICHTE DER BUNSEN-GESELLSCHAFT-PHYSICAL CHEMISTRY CHEMICAL PHYSICS | 1994年 / 98卷 / 12期

关键词：

BIOPHYSICAL CHEMISTRY; HIGH PRESSURE; MEMBRANES; PHASE TRANSITIONS; PHOSPHOLIPID MIXTURES;

D O I：

10.1002/bbpc.19940981213

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

High pressure differential thermal analysis (DTA) has been applied to the study of the temperature-composition-pressure phase diagram of the binary saturated phospholipid mixtures dimyristoyl/palmitoyl phosphatidylcholine (DMPC/DPPC) and dimyristoyl/stearoyl phosphatidylcholine (DMPC/DPPC) in excess water. A temperature range from 10 to 100-degrees-C and a pressure range from ambient up to 1500 bar has been covered. The experimentally obtained phase equilibria of these binary systems are compared with thermodynamic calculations for ideal and non-ideal mixing behaviour, and with recent results from Monte Carlo computer simulation studies, which not only permit determination of the phase diagram but also reveal a pictorial view of the local structure of the mixtures in the different parts of the phase diagrams.

引用

页码：1585 / 1589

页数：5