ANTI-ANNEXIN-V ANTIBODY IN SYSTEMIC LUPUS-ERYTHEMATOSUS PATIENTS WITH LUPUS ANTICOAGULANT AND/OR ANTICARDIOLIPIN ANTIBODY

被引：116

作者：

MATSUDA, J

SAITOH, N

GOHCHI, K

GOTOH, M

TSUKAMOTO, M

机构：

[1] Department of Medicine, Teikyo University School of Medicine, Tokyo

来源：

AMERICAN JOURNAL OF HEMATOLOGY | 1994年 / 47卷 / 01期

关键词：

ANTI-ANNEXIN V ANTIBODY; ANTICARDIOLIPIN ANTIBODY; LUPUS ANTICOAGULANT; BETA(2)-GLYCOPROTEIN 1;

D O I：

10.1002/ajh.2830470112

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We investigated anti-annexin V antibody (aANX) in patients with systemic lupus erythematosus (SLE), and correlated to positivity with lupus anticoagulant (LA)/anticardiolipin antibody (aCL). aANX was positive in 12/47 SLE patients (26%), including 7 with beta(2)-glycoprotein 1 (GPI)-dependent aANX. The positivity of aANX was higher in patients with aCL (19%) and LA/aCL (50%) than in those without LA/aCL (10%). From these results, it is concluded that aANX is an autoantibody closely related to LA/aCL, and can be a possible new risk marker for thrombosis. (C) 1994 Wiley-Liss, Inc.

引用

页码：56 / 58

页数：3

共 8 条

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