HIGHLY SELECTIVE ASYMMETRIC HYDROLYSIS OF 2,2-DISUBSTITUTED EPOXIDES USING LYOPHILIZED CELLS OF RHODOCOCCUS SP NCIMB-11216

被引：26

作者：

WANDEL, U ^{[1
]}

MISCHITZ, M ^{[1
]}

KROUTIL, W ^{[1
]}

FABER, K ^{[1
]}

机构：

[1] GRAZ UNIV TECHNOL,INST ORGAN CHEM,A-8010 GRAZ,AUSTRIA

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1995年 / 07期

关键词：

D O I：

10.1039/p19950000735

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(+/-)-2-Methyl-2-alkyl epoxides have been resolved by biocatalytic hydrolysis employing lyophilized cells of Rhodococcus sp. NCIMB 11216. The reaction has been shown to proceed with retention of configuration leading to (S)-1,2-diols and (R)-epoxides with excellent selectivities(E > 100).

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页码：735 / 736

页数：2

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