THE CONTROL OF APOPTOSIS IN MAMMALIAN-CELLS

被引：138

作者：

COLLINS, MKL ^{[1
]}

RIVAS, AL ^{[1
]}

机构：

[1] CSIC, INST PARASITOL LOPEZ NEYRA, E-18001 GRANADA, SPAIN

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1993年 / 18卷 / 08期

关键词：

D O I：

10.1016/0968-0004(93)90042-L

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This article summarizes what is now known, more than 100 years after this prescient observation, of the mechanisms by which death of mammalian cells is regulated. Particular attention is paid to the elimination of self-reactive thymocytes, the induction of cell death during cancer therapy and the mechanism(s) by which cells die following growth factor removal.

引用

页码：307 / 309

页数：3

共 31 条

[11] INDUCTION OF BCL-2 EXPRESSION BY EPSTEIN-BARR-VIRUS LATENT MEMBRANE PROTEIN-1 PROTECTS INFECTED B-CELLS FROM PROGRAMMED CELL-DEATH [J].

HENDERSON, S ;

ROWE, M ;

GREGORY, C ;

CROOMCARTER, D ;

WANG, F ;

LONGNECKER, R ;

KIEFF, E ;

RICKINSON, A .

CELL, 1991, 65 (07) :1107-1115

[12] BCL-2 IS AN INNER MITOCHONDRIAL-MEMBRANE PROTEIN THAT BLOCKS PROGRAMMED CELL-DEATH [J].

HOCKENBERY, D ;

NUNEZ, G ;

MILLIMAN, C ;

SCHREIBER, RD ;

KORSMEYER, SJ .

NATURE, 1990, 348 (6299) :334-336

[13] BCL-2 BLOCKS APOPTOSIS IN CELLS LACKING MITOCHONDRIAL-DNA [J].

JACOBSON, MD ;

BURNE, JF ;

KING, MP ;

MIYASHITA, T ;

REED, JC ;

RAFF, MC .

NATURE, 1993, 361 (6410) :365-369

[14]

JONES DP, 1989, J BIOL CHEM, V264, P6398

[15] ACTIVATION OF PROGRAMMED CELL-DEATH IN THE RAT VENTRAL PROSTATE AFTER CASTRATION [J].

KYPRIANOU, N ;

ISAACS, JT .

ENDOCRINOLOGY, 1988, 122 (02) :552-562

[16] CANCER - A DEATH IN THE LIFE OF P53 [J].

LANE, DP .

NATURE, 1993, 362 (6423) :786-787

[17] CONVERSION OF LYTIC TO PERSISTENT ALPHAVIRUS INFECTION BY THE BCL-2 CELLULAR ONCOGENE [J].

LEVINE, B ;

HUANG, Q ;

ISAACS, JT ;

REED, JC ;

GRIFFIN, DE ;

HARDWICK, JM .

NATURE, 1993, 361 (6414) :739-742

[18] MECHANISM OF ANTIGEN-DRIVEN SELECTION IN GERMINAL-CENTERS [J].

LIU, YJ ;

JOSHUA, DE ;

WILLIAMS, GT ;

SMITH, CA ;

GORDON, J ;

MACLENNAN, ICM .

NATURE, 1989, 342 (6252) :929-931

[19]

MACAULAY VM, 1990, CANCER RES, V50, P2511

[20] DEATH OF MATURE T-CELLS BY SEPARATE LIGATION OF CD4 AND THE T-CELL RECEPTOR FOR ANTIGEN [J].

NEWELL, MK ;

HAUGHN, LJ ;

MAROUN, CR ;

JULIUS, MH .

NATURE, 1990, 347 (6290) :286-289

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