EVALUATION OF MIXED-MODE STATIONARY PHASES IN LIQUID-CHROMATOGRAPHY FOR THE SEPARATION OF CHARGED AND UNCHARGED OLIGOMER-LIKE MODEL COMPOUNDS

被引：26

作者：

ELEVELD, JT

CLAESSENS, HA

AMMERDORFFER, JL

VANHERK, AM

CRAMERS, CA

机构：

[1] EINDHOVEN UNIV TECHNOL,INSTRUMENTAL ANAL LAB,5600 MB EINDHOVEN,NETHERLANDS

[2] EINDHOVEN UNIV TECHNOL,POLYMER CHEM LAB,5600 MB EINDHOVEN,NETHERLANDS

来源：

JOURNAL OF CHROMATOGRAPHY A | 1994年 / 677卷 / 02期

关键词：

D O I：

10.1016/0021-9673(94)80150-9

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The possibility to separate charged and uncharged oligomer-like test compounds by high-performance liquid chromatography was investigated, using mixed-mode (reversed-phase/anion-exchange) stationary phases. In order to examine this possibility, several columns were evaluated for their reversed-phase, anion-exchange and mixed-mode properties using neutral and charged model compounds. The OmniPac PAX-500, the PRP-X100 and the mixed-phase PLRP-S/PL-SAX columns showed promising results for the separation of real samples.

引用

页码：211 / 227

页数：17

共 42 条

[11] GROUP CONTRIBUTIONS TO HYDROPHOBICITY AND ELUTION BEHAVIOR OF PYRIDINE-DERIVATIVES IN REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].