STUDIES ON BETA-LACTAMS

被引:8
作者
CHATTERJEE, BG
ABDULLA, RF
机构
[1] Department of Applied Chemistry, Indian Institute of Technology, Kharagpur, W. Bengal
来源
ZEITSCHRIFT FUR NATURFORSCHUNG PART B-CHEMIE BIOCHEMIE BIOPHYSIK BIOLOGIE UND VERWANDTEN GEBIETE | 1969年 / B 24卷 / 09期
关键词
D O I
10.1515/znb-1969-0909
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Since the discovery11 of the activating effect of the N-(p-Nitro-phenyl)-group on the methine hydrogen of halogenacetamino esters, it has been found that the p-Acetyl-phenyl and m-Nitro-phenyl groups exert a similar effect. It has been shown that the delocalisation of the N-non-bonded electrons across the orbitals of the N-Aryl substituent is the governing factor in the cyclisation of the above systems, and the effect of the bulk of the N-Aryl substituent is relegated to a minor position. © 1969, Walter de Gruyter. Alle Rechte vorbehalten.
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页码:1120 / +
页数:1
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