HYDRATION OF DNA BASES - ANALYSIS OF CRYSTALLOGRAPHIC DATA

被引：127

作者：

SCHNEIDER, B ^{[1
]}

COHEN, D ^{[1
]}

BERMAN, HM ^{[1
]}

机构：

[1] RUTGERS STATE UNIV,DEPT COMP SCI,NEW BRUNSWICK,NJ 08903

来源：

BIOPOLYMERS | 1992年 / 32卷 / 07期

关键词：

D O I：

10.1002/bip.360320703

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We present a systematic analysis of water structure around nucleic acid bases. We have examined 28 crystal structures of oligonucleotides, and have studied the patterns of water around the four bases, guanine, cytosine, adenine, and thymine. The geometries of water positions were calculated up to 4.00 angstrom from base atoms. We have found conformation-dependent differences in both the geometry and extent of hydration of the bases.

引用

页码：725 / 750

页数：26

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