MARBURG AGENT DISEASE - IN MONKEYS

The experimental infection of vervet, rhesus and squirrel monkeys is described. All the monkeys developed a uniformly fatal illness irrespective of the dose or route of infection. In the early stages of illness the animals appeared to be quite healthy, but after incubation periods of 6–13 days they rapidly deteriorated. A petechial skin rash was frequently seen in the later stages of illness. The infectious agent was detected in monkeys' blood, saliva, and urine, often in considerable quantities. © 1969 Royal Society of Tropical Medicine and Hygiene.