MEASUREMENT OF OPTICAL-PROPERTIES OF BIOLOGICAL TISSUES BY LOW-COHERENCE REFLECTOMETRY

被引：308

作者：

SCHMITT, JM ^{[1
]}

KNUTTEL, A ^{[1
]}

BONNER, RF ^{[1
]}

机构：

[1] NHLBI, CARDIAC ENERGET LAB, BETHESDA, MD 20892 USA

来源：

APPLIED OPTICS | 1993年 / 32卷 / 30期

关键词：

INTERFEROMETRY; LOW COHERENCE; BIOMEDICAL OPTICS;

D O I：

10.1364/AO.32.006032

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We show that optical properties of dense biological tissues can be determined from backscattered power curves measured by a low-coherence reflectometer. Our measurement approach is based on a first-order scattering theory that relates the backscattered power to the total and backscattering cross sections of scatterers in a turbid medium. As a validation of the technique, measurements were made with a commercially available reflectometer on suspensions of polystyrene microspheres having known optical properties. With this reflectometer, which employs a 1300-nm LED source that emits less than 20 muW, we found that skin tissues could be probed to a depth of nearly 1 mm. Estimates of optical coefficients of human dermis and of a variety of excised animal tissues are given.

引用

页码：6032 / 6042

页数：11

共 31 条

[1] FIRST-ORDER AND SECOND-ORDER BACKSCATTERING FROM CLOUDS ILLUMINATED BY FINITE BEAMS [J].