PARTITION DATA OF PENICILLINS DETERMINED BY MEANS OF REVERSED-PHASE THIN-LAYER CHROMATOGRAPHY

被引：259

作者：

BIAGI, GL

BARBARO, AM

GAMBA, MF

GUERRA, MC

机构：

[1] Istituto di Farmacologia, Farmacognosia dell'Università di Bologna

来源：

JOURNAL OF CHROMATOGRAPHY | 1969年 / 41卷 / 3-4期

关键词：

D O I：

10.1016/0021-9673(64)80150-3

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The RM values of II penicillins were measured by means of a reversed-phase thin-layer chromatographic method with various concentrations of acetone in the mobile phase. RM values were calculated by interpolation or extrapolation from the ranges of linearity between RM values and composition of the mobile phase. The influence of substituent groups on the RM values of the penicillins and disagreement with Σπ values are pointed out. © 1969.

引用

页码：371 / &

共 29 条

[11] DANIELS TC, 1966, TEXTBOOK ORGANIC MED, P4
[12] NEW SUBSTITUENT CONSTANT PI DERIVED FROM PARTITION COEFFICIENTS
FUJITA, T
HANSCH, C
IWASA, J
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1964, 86 (23) : 5175 - &
[13] STRUCTURE-ACTIVITY RELATIONSHIP IN PENICILLINS
HANSCH, C
DEUTSCH, EW
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1965, 8 (05) : 705 - &
[14] HANSCH C, 1965, MOL PHARMACOL, V1, P205
[15] USE OF SUBSTITUENT CONSTANTS IN ANALYSIS OF STRUCTURE-ACTIVITY RELATIONSHIP IN PENICILLIN DERIVATIVES
HANSCH, C
STEWARD, AR
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1964, 7 (06) : 691 - &
[16] RHO-SIGMA-PI ANALYSIS . METHOD FOR CORRELATION OF BIOLOGICAL ACTIVITY + CHEMICAL STRUCTURE
HANSCH, C
FUJITA, T
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1964, 86 (08) : 1616 - &
[17] CORRELATION OF BIOLOGICAL ACTIVITY OF PLANT GROWTH REGULATORS AND CHLOROMYCETIN DERIVATIVES WITH HAMMETT CONSTANTS AND PARTITION COEFFICIENTS
HANSCH, C
STREICH, M
GEIGER, F
MUIR, RM
MALONEY, PP
FUJITA, T
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1963, 85 (18) : 2817 - +
[18] USE OF SUBSTITUENT CONSTANTS IN CORRELATION OF DEMETHYLATION RATES
HANSCH, C
STEWARD, AR
IWASA, J
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1965, 8 (06) : 868 - &
[19] SUBSTITUENT CONSTANTS FOR ALIPHATIC FUNCTIONS OBTAINED FROM PARTITION COEFFICIENTS
IWASA, J
FUJITA, T
HANSCH, C
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1965, 8 (02) : 150 - &
[20] KAUFMANN HP, 1961, FETT SEIFEN ANSTR, V63, P828

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