ATROPHY OF THE IPSILATERAL SUBSTANTIA NIGRA FOLLOWING MIDDLE CEREBRAL-ARTERY OCCLUSION IN THE RAT

被引：130

作者：

TAMURA, A

KIRINO, T

SANO, K

TAKAGI, K

OKA, H

机构：

[1] Department of Neurosurgery, Teikyo University School of Medicine, Tokyo

来源：

BRAIN RESEARCH | 1990年 / 510卷 / 01期

关键词：

Atrophy; Ischemia; Middle cerebral artery; Rat; Substantia nigra; γ-Aminobutyric acid;

D O I：

10.1016/0006-8993(90)90744-V

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Following occlusion of the left middle cerebral artery in the rat, marked atrophy was observed in the ipsilateral substantia nigra in and after the second week. The mechanism of this neuropathological change in the substantia nigra, which is remote from the site of infarction, may be explained by transsynaptic, neurotransmitter-mediated disinhibition as a result of infarction of the striatum. © 1990.

引用

页码：154 / 157

页数：4

共 14 条

[11]

TAMURA A, 1984, Nippon Acta Radiologica, V44, P1546

[12] FOCAL CEREBRAL-ISCHEMIA IN THE RAT .2. REGIONAL CEREBRAL BLOOD-FLOW DETERMINED BY [IODOANTIPYRINE-C-14 AUTORADIOGRAPHY FOLLOWING MIDDLE CEREBRAL-ARTERY OCCLUSION [J].