EFFECT OF PERHEXILINE-MALEATE ON LIPID-METABOLISM IN THE RAT .2. LIVER AND LUNG PHOSPHOLIPIDS AFTER ADMINISTRATION OF HIGH-DOSES OF PERHEXILINE-MALEATE

被引：3

作者：

HOENIG, V ^{[1
]}

WERNER, F ^{[1
]}

机构：

[1] HOP CIVIL,MED B CLIN,F-67000 STRASBOURG,FRANCE

来源：

PHARMACOLOGICAL RESEARCH COMMUNICATIONS | 1979年 / 11卷 / 06期

关键词：

D O I：

10.1016/S0031-6989(79)80023-5

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Short-term administration of high doses of the antianginal drug perhexiline maleate to rats produces an increase in liver and lung phospholipids. This increase is accompanied by alterations of phospholipid composition which tend to change in opposite directions in the two organs. After chronic treatment with the drug, the increase is still apparent in the liver but no longer in the lung, and the composition of phospholipids tends to become normal. © 1979 The Italian Pharmacological Society.

引用

页码：509 / 515

页数：7

共 19 条

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NEWBERNE JW, 1978, COMMUNICATION

[12] QUANTITATIVE ANALYSIS OF PHOSPHOLIPIDS BY THIN-LAYER CHROMATOGRAPHY AND PHOSPHORUS ANALYSIS OF SPOTS [J].