URINARY-INFECTION, REFLUX AND RENAL SCARRING IN FEMALES CONTINUOUSLY FOLLOWED FOR 13-38 YEARS

被引：74

作者：

MARTINELL, J

CLAESSON, I

LIDINJANSON, G

JODAL, U

机构：

[1] Department of Paediatrics, Gothenburg University, East Hospital, Gothenburg

[2] Department of Paediatric Radiology, Gothenburg University, East Hospital, Gothenburg

[3] Department of Infectious Diseases, Gothenburg University, East Hospital, Gothenburg

来源：

PEDIATRIC NEPHROLOGY | 1995年 / 9卷 / 02期

关键词：

REFLUX NEPHROPATHY; PYELONEPHRITIS; URINARY TRACT INFECTION; FEMALES; FOLLOW-UP;

D O I：

10.1007/BF00860724

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

This study describes the pattern of urinary tract infections (UTI) in 87 females prospectively followed for a median of 23 years from their first recognized symptomatic infection in childhood, At 16 years of age they were selected for follow-up into adulthood because of renal scarring (reflux nephropathy) in 45 and recurrent UTI in 42. The attack rate (number of urinary tract infections per individual per observation year) was highest during the Ist year of life (1.9), with a gradual decrease to the lowest rate (0.2) at age 11-15 years, A moderately increased attack rate (0.4), was seen in the late teens, extending through to the mid twenties. The proportion of infections having a pyelonephritic character decreased with age and number of infection episodes, but not in females with severe renal scarring, Pyelonephritic infections were correlated with vesicoureteric reflux, and renal scarring to low age at the index infection, total number of pyelonephritic episodes and reflux. Females with renal scarring continued to have a high proportion of pyelonephritic recurrences after 10 years of age, implying that they risk progressive renal disease and should be closely followed into adulthood.

引用

页码：131 / 136

页数：6

共 23 条

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