N-AND N'-ARYL SUBSTITUTION IN BENZAMIDINES

被引：13

作者：

SMITH, JA

TAYLOR, H

机构：

[1] Department of Pharmaceutical Chemistry, School of Pharmacy

来源：

JOURNAL OF THE CHEMICAL SOCIETY B-PHYSICAL ORGANIC | 1969年 / 01期

关键词：

D O I：

10.1039/j29690000066

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

N-Phenyl substitution of amino- and imino-groups in benzamidines is shown to reduce basic strength by factors of ca. 10 and 1000, respectively. The configuration of the imino-N-phenyl ring is discussed. The structure of the predominant tautomer of N-(3-diethylaminopropyl)-N′-phenylbenzamidine is indicated.

引用

页码：66 / &

共 10 条

[1] THE CHEMOTHERAPY OF TUBERCULOSIS .4. SOME N-SUBSTITUTED NICOTINAMIDES AND NICOTINAMIDINES
BAXTER, JN
CYMERMANCRAIG, J
[J]. JOURNAL OF THE CHEMICAL SOCIETY, 1953, (MAY): : 1490 - 1493
[2] THE BASIC STRENGTHS OF SOME N-4-DIPHENYLYLAMIDINES
CARSWELL, DJ
CYMERMAN, J
LYONS, LE
[J]. JOURNAL OF THE CHEMICAL SOCIETY, 1952, (FEB): : 430 - 432
[3] PARTITION COEFFICIENTS OF SOME AMIDINES
CYMERMANCRAIG, J
PARKER, MJ
WOODHOUSE, P
[J]. JOURNAL OF THE CHEMICAL SOCIETY, 1953, (OCT): : 3050 - 3052
[4] REACTION OF TRICHLOROACETONITRILE WITH PRIMARY AND SECONDARY AMINES .3. STRUCTURE OF AMIDINIUM CATION IN THE LIGHT OF INFRARED STUDY
GRIVAS, JC
TAURINS, A
[J]. CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1959, 37 (08): : 1260 - 1265
[5] N,N-DISUBSTITUTED AMIDINES .2. BENZAMIDINES - THE EFFECT OF SUBSTITUTION ON BASICITY
LORZ, E
BALTZLY, R
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1949, 71 (12) : 3992 - 3994
[6] STRUCTURE OF N-MONO AND N,N'-DISUBSTITUTED AMIDINES
PREVORSEK, D
[J]. JOURNAL OF PHYSICAL CHEMISTRY, 1962, 66 (05) : 769 - &
[7] PYMAN FL, 1923, J CHEM SOC, P367
[8] SYNTHESIS OF N-SUBSTITUTED AMIDINES OF POTENTIAL PHARMACOLOGICAL ACTIVITY
SMITH, JA
TAYLOR, H
[J]. JOURNAL OF PHARMACY AND PHARMACOLOGY, 1963, 15 (08) : 548 - &
[9] N-AND N'-ARYL SUBSTITUTION IN BENZAMIDINES
SMITH, JA
TAYLOR, H
[J]. JOURNAL OF THE CHEMICAL SOCIETY B-PHYSICAL ORGANIC, 1969, (01): : 66 - &
[10] WEPSTER BM, 1952, RECL TRAV CHIM PAY B, V71, P1171

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