ROLE OF VAGUS NERVES IN VENTILATORY RESPONSES TO HYPERCAPNIA AND HYPOXIA IN ANAESTHETIZED AND UNANAESTHETIZED RABBITS

被引：114

作者：

RICHARDSON, PS

WIDDICOMBE, JG

机构：

[1] University Laboratory of Physiology, Oxford, England

来源：

RESPIRATION PHYSIOLOGY | 1969年 / 7卷 / 01期

关键词：

Breuer-Hering reflexes; Control of breathing; Vagotomy; Ventilatory response to CO[!sub]2[!/sub;

D O I：

10.1016/0034-5687(69)90073-5

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Minute volume/end-tidal Pco2 relationships have been determined for anaesthetized and unanaesthetized rabbits, before and after bilateral cervical vagotomy. Vagotomy depresses and flattens the upper parts of the curves (i.e., the ventilatory response to CO2 is reduced), whether the inspired CO2 mixture is in air, 100% O2 or 8-10% O2. The increase in frequency of breathing due to CO2 is especially depressed. During the maximal response to CO2 the vagotomized rabbits are able to increase ventilation in response to other stimuli. It is concluded that a lung reflex or reflexes is partly responsible for the shape of the minute volume/Pco2; curve in rabbits with intact vagi. © 1969.

引用

页码：122 / +

页数：1

共 19 条

[11] RAMOS JG, 1956, AM REV TUBERC PULM, V73, P519
[12] RICHARDSON PS, 1965, J PHYSIOL-LONDON, V181, pP43
[13] RESPIRATORY REFLEXES ACTING ON DIAPHRAGM AND INSPIRATORY INTERCOSTAL MUSCLES OF RABBIT
SANTAMBROGIO, G
WIDDICOMBE, JG
[J]. JOURNAL OF PHYSIOLOGY-LONDON, 1965, 180 (04): : 766 - +
[14] SASAKI SHOSETSU, 1927, JOUR BIOPHYSICS, V2, P197
[15] Scott FH, 1908, J PHYSIOL-LONDON, V37, P301
[16] STEIN J, 1965, THESIS OXFORD U
[17] RECEPTORS IN THE TRACHEA AND BRONCHI OF THE CAT
WIDDICOMBE, JG
[J]. JOURNAL OF PHYSIOLOGY-LONDON, 1954, 123 (01): : 71 - 104
[18] WIEMER W, 1965, PFLUG ARCH GES PHYS, V283, pR46
[19] INTERRELATION BETWEEN LUNG VOLUME ARTERIAL CO2 TENSION AND RESPIRATORY ACTIVITY
WOLDRING, S
[J]. JOURNAL OF APPLIED PHYSIOLOGY, 1965, 20 (04) : 647 - &

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