ENHANCED FETAL HEMOGLOBIN PRODUCTION BY PHENYLACETATE AND 4-PHENYLBUTYRATE IN ERYTHROID PRECURSORS DERIVED FROM NORMAL DONORS AND PATIENTS WITH SICKLE-CELL-ANEMIA AND BETA-THALASSEMIA

被引：108

作者：

FIBACH, E

PRASANNA, P

RODGERS, GP

SAMID, D

机构：

[1] NCI,CLIN PHARMACOL BRANCH,BLDG 10,ROOM 12C103,BETHESDA,MD 20892

[2] HADASSAH UNIV HOSP,DEPT HEMATOL,JERUSALEM,ISRAEL

[3] NIDDKD,CHEM BIOL LAB,BETHESDA,MD

来源：

BLOOD | 1993年 / 82卷 / 07期

关键词：

D O I：

10.1182/blood.V82.7.2203.bloodjournal8272203

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

引用

页码：2203 / 2209

页数：7

共 40 条

[1]

ALTER BP, 1979, EXP HEMATOL, V7, P200

[2]

[Anonymous], 1986, HEMOGLOBIN MOL GENET

[3]

PHENYLACETYLGLUTAMINE MAY REPLACE UREA AS A VEHICLE FOR WASTE NITROGEN-EXCRETION [J].

BRUSILOW, SW .

PEDIATRIC RESEARCH, 1991, 29 (02) :147-150

[4]

TREATMENT OF EPISODIC HYPERAMMONEMIA IN CHILDREN WITH INBORN-ERRORS OF UREA SYNTHESIS [J].

BRUSILOW, SW ;

DANNEY, M ;

WABER, LJ ;

BATSHAW, M ;

BURTON, B ;

LEVITSKY, L ;

ROTH, K ;

MCKEETHREN, C ;

WARD, J .

NEW ENGLAND JOURNAL OF MEDICINE, 1984, 310 (25) :1630-1634

[5]

CARR BI, 1984, CARCINOGENESIS, V5, P1584

[6]

CHARACHE S, 1992, BLOOD, V79, P2555

[7]

TREATMENT OF SICKLE-CELL-ANEMIA WITH 5-AZACYTIDINE RESULTS IN INCREASED FETAL HEMOGLOBIN PRODUCTION AND IS ASSOCIATED WITH NONRANDOM HYPOMETHYLATION OF DNA AROUND THE GAMMA-DELTA-BETA-GLOBIN GENE-COMPLEX [J].

CHARACHE, S ;

DOVER, G ;

SMITH, K ;

TALBOT, CC ;

MOYER, M ;

BOYER, S .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (15) :4842-4846

[8]

5-AZACYTIDINE STIMULATES FETAL HEMOGLOBIN-SYNTHESIS IN ANEMIC BABOONS [J].

DESIMONE, J ;

HELLER, P ;

HALL, L ;

ZWIERS, D .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (14) :4428-4431

[9]

DOVER GJ, 1992, NEW ENGL J MED, V327, P569

[10]

DOVER GJ, 1992, BLOOD, V80, pA73

← 1 2 3 4 →