CHEMICALLY-INDUCED HYPOTHYROIDISM PRODUCES ELEVATED AMOUNTS OF THE ALPHA-SUBUNIT OF THE INHIBITORY GUANINE-NUCLEOTIDE BINDING-PROTEIN (GI) AND THE BETA-SUBUNIT COMMON TO ALL G-PROTEINS

被引：73

作者：

MILLIGAN, G

SPIEGEL, AM

UNSON, CG

SAGGERSON, ED

机构：

[1] UNIV GLASGOW,DEPT PHARMACOL,GLASGOW G12 8QQ,SCOTLAND

[2] ROCKEFELLER UNIV,DEPT BIOCHEM,NEW YORK,NY 10021

[3] UNIV LONDON UNIV COLL,DEPT BIOCHEM,LONDON WC1E 6BT,ENGLAND

[4] NIDDKD,METAB DIS BRANCH,BETHESDA,MD 20892

来源：

BIOCHEMICAL JOURNAL | 1987年 / 247卷 / 01期

关键词：

D O I：

10.1042/bj2470223

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：223 / 227

页数：5

共 26 条

[1]

CHOHAN P, 1984, BIOCHEM J, V223, P53, DOI 10.1042/bj2230053

[2] HUMAN-GI PROTEIN ALPHA-SUBUNIT - DEDUCTION OF AMINO-ACID STRUCTURE FROM A CLONED CDNA [J].

DIDSBURY, JR ;

HO, YS ;

SNYDERMAN, R .

FEBS LETTERS, 1987, 211 (02) :160-164

[3] DETECTION OF THE MAJOR PERTUSSIS TOXIN SUBSTRATE OF HUMAN-LEUKOCYTES WITH ANTISERA RAISED AGAINST SYNTHETIC PEPTIDES [J].

FALLOON, J ;

MALECH, H ;

MILLIGAN, G ;

UNSON, C ;

KAHN, R ;

GOLDSMITH, P ;

SPIEGEL, A .

FEBS LETTERS, 1986, 209 (02) :352-356

[4]

FUNG BKK, 1985, MOL MECHANISMS TRANS, V4, P183

[5] ABOLITION OF THE EXPRESSION OF INHIBITORY GUANINE-NUCLEOTIDE REGULATORY PROTEIN-GI ACTIVITY IN DIABETES [J].

GAWLER, D ;

MILLIGAN, G ;

SPIEGEL, AM ;

UNSON, CG ;

HOUSLAY, MD .

NATURE, 1987, 327 (6119) :229-232

[6] USE OF SPECIFIC ANTIBODIES TO QUANTITATE THE GUANINE NUCLEOTIDE-BINDING PROTEIN-G0 IN BRAIN [J].

GIERSCHIK, P ;

MILLIGAN, G ;

PINES, M ;

GOLDSMITH, P ;

CODINA, J ;

KLEE, W ;

SPIEGEL, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (07) :2258-2262

[7] CHANGES IN THE GUANINE NUCLEOTIDE-BINDING PROTEINS, GI AND GO, DURING DIFFERENTIATION OF 3T3-L1 CELLS [J].

GIERSCHIK, P ;

MORROW, B ;

MILLIGAN, G ;

RUBIN, C ;

SPIEGEL, A .

FEBS LETTERS, 1986, 199 (01) :103-106

[8]

GOLDSMITH P, 1987, IN PRESS J BIOL CHEM

[9] ENZYMES INVOLVED IN ADENOSINE METABOLISM IN RAT WHITE AND BROWN ADIPOCYTES - EFFECTS OF STREPTOZOTOCIN-DIABETES, HYPOTHYROIDISM, AGE AND SEX-DIFFERENCES [J].

JAMAL, Z ;

SAGGERSON, ED .

BIOCHEMICAL JOURNAL, 1987, 245 (03) :881-886

[10] FRACTIONATION OF NUCLEI FROM MAMMALIAN CELLS BY ZONAL CENTRIFUGATION [J].

JOHNSTON, IR ;

MATHIAS, AP ;

PENNINGTON, F ;

RIDGE, D .

BIOCHEMICAL JOURNAL, 1968, 109 (01) :127-+

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