ACTIVATED CHARCOAL-MEDIATED HYDROXYLATION UNDER VERY MILD CONDITIONS - CONVERSION OF PHYSALIN-B INTO 25-HYDROXYPHYSALIN-B

被引：7

作者：

MAKINO, B

KAWAI, M

YAMAMOTO, T

YAMAMURA, H

BUTSUGAN, Y

HAYASHI, M

OGAWA, K

机构：

[1] NAGOYA INST TECHNOL,DEPT APPL CHEM,GOKISO CHO,SHOWA KU,NAGOYA,AICHI 466,JAPAN

[2] ASAHI CHEM IND CO LTD,INST LIFE SCI RES,SHIZUOKA 41023,JAPAN

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1992年 / 19期

关键词：

D O I：

10.1039/c39920001430

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Activated charcoal treatment of physalin B, a 13,14-seco-16,24-cyclosteroidal constituent of Physalis alkekengi, in MeOH at room temperature yields a product possessing a hydroxy group at the alpha-position of the delta-lactone carbonyl function, namely 25-hydroxyphysalin B, in high yield.

引用

收藏

页码：1430 / 1431

页数：2

相关论文

共 8 条

[1] CARBON AS ADSORBENT AND CATALYST [J].

COUGHLIN, RW .

INDUSTRIAL & ENGINEERING CHEMISTRY PRODUCT RESEARCH AND DEVELOPMENT, 1969, 8 (01) :12-&

[2] A ONE-STEP PROCEDURE FOR PREPARATION OF TERTIARY ALPHA-KETOLS FROM CORRESPONDING KETONES [J].

GARDNER, JN ;

CARLON, FE ;

GNOJ, O .

JOURNAL OF ORGANIC CHEMISTRY, 1968, 33 (08) :3294-&

[3] STRUCTURE OF PHYSALIN C - A BITTER PRINCIPLE OF PHYSALIS-ALKEKENGI-VAR-FRANCHETI [J].

KAWAI, M ;

MATSUURA, T .

TETRAHEDRON, 1970, 26 (07) :1743-&

[4] A NEW PHYSALIN FROM PHYSALIS-ALKEKENGI - STRUCTURE OF PHYSALIN-L [J].

KAWAI, M ;

MATSUURA, T ;

KYUNO, S ;

MATSUKI, H ;

TAKENAKA, M ;

KATSUOKA, T ;

BUTSUGAN, Y ;

SAITO, K .

PHYTOCHEMISTRY, 1987, 26 (12) :3313-3317

[5]

KAWAI M, 1992, IN PRESS PHYOCHEMIST, V31

[6]

KAWAI M, 1988, B CHEM SOC JPN, V61, P2969

[7] STRUCTURES OF PHYSALIN-A AND PHYSALIN-B, 13,14-SECO-16,24-CYCLO-STEROIDS FROM PHYSALIS-ALKEKENGI VAR FRANCHETI [J].

MATSUURA, T ;

KAWAI, M ;

NAKASHIM.R ;

BUTSUGAN, Y .

JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC, 1970, (05) :664-&

[8] OXIDATION OF CYCLOHEXENE CATALYZED BY COBALT ION SUPPORTED ON CARBON [J].

TOMITA, A ;

MORI, S ;

TAMI, Y .

JOURNAL OF CATALYSIS, 1971, 23 (01) :141-&