FERTILIZATION INVITRO OF SUPERNUMERARY OOCYTES FOLLOWING GAMETE INTRAFALLOPIAN TRANSFER (GIFT)

被引：2

作者：

CRITCHLOW, JD

MATSON, PL

TROUP, SA

IBRAHIM, ZHZ

BURSLEM, RW

BUCK, P

LIEBERMAN, BA

机构：

[1] Regional IVF Unit, St Mary's Hospital, Manchester M13 0JH, Whitworth Park

[2] Manchester Fertility Services Ltd, Manchester BUPA Hospital, Manchester M16 8AJ, Russell Road, Whalley Range

来源：

HUMAN REPRODUCTION | 1990年 / 5卷 / 07期

关键词：

GIFT; IVF; Supernumerary oocytes;

D O I：

10.1093/oxfordjournals.humrep.a137197

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Gamete intra-Fallopian transfer (GIFT) was performed in 130 treatment cycles over a 17-month period. In 91% (118/130) of the cycles one or more oocytes were available for insemination in vitro and only GIFT cycles with supernumerary oocytes were included in the present study. Pituitary and ovarian suppression was arhieved with buserelin followed by stimulation of multifollicular development by human menopausal gonadotrophin (HMG). Failure of supernumerary oocytes to fertilize was associated with a significantly reduced pregnancy rate (3/23; 13%) compared to cycles where fertilization occurred in vitro (35/95; 37%). These findings demonstrate that the outcome of IVF of supernumerary oocytes may be of particular diagnostic value in couples where the female partner has not conceived following treatment by GIFT after pituitary down-regulation with buserelin and ovarian stimulation with HMG. © 1990 Oxford University Press.

引用

页码：853 / 856

页数：4

共 27 条

[1]

Abdalla H.I., Ahuja K.K., Leonard T., Morris N.N., The value of IVF-ET in patients undergoing treatment by the GIFT procedure, Hum. Reprod, 8, pp. 944-947, (1988)

[2]

Abdalla H.I., Baber R., Leonard T., Kirkland A., Power M., Studd J., The Prognostic Value of the Number of Oocytes Collected and the in Vitro Fertilization Rate of Extra Oocytes in a GIFT Cycle, (1989)

[3]

Asch R.H., Ellsworth L.R., Balmaceda J.R., Wong P.C., Pregnancy after translaparoscopic gamete intrafallopian transfer, Lancet, 2, pp. 1034-1035, (1984)

[4]

Clarke G.N., Lopata A., McBain J.C., Baker H., Johnston W., Effect of sperm antibodies in males on human in-vitro fertilization (IVF), Am J. Reprod. Immunol. Microbiol, 8, pp. 62-66, (1985)

[5]

Conaghan J., Dimitry E.S., Mills H., Margara R.A., Winston R., Delayed human chorionic gonadotrophin administration for in-vitro fertilization, Lancet, 1, pp. 1323-1324, (1989)

[6]

Corson S., Batzer F., Eisenberg E., English M., White S., Laberge Y., Go K.J., Early experience with the GIFT procedure, J. Reprod. Med, 31, pp. 219-223, (1986)

[7]

Craft I., Brinsden P.R., Simons E.G., Lewis P.M., Limitations of GIFT, Lancet, 1, (1988)

[8]

Critchlow J.D., Matson P.L., Troup S.A., Home G., Morroll D.R., Izzard H., Cryopreservation of Human Embryos at the Pronuclear, Early Cleavage Or Blastocyst Stage, (1989)

[9]

Devroey P., Braekmans P., Smitz J., Van Wasberghe L., Wisanto A., Van Steirteghem A., Heytens L., Camu F., Pregnancy after translaparoscopic zygote intrafallopian transfer in a patient with antisperm antibodies, Lancet, 1, (1986)

[10]

Fishel S., Faratian B., Webster J., Jackson P., Offering GIFT in an IVF Unit, Fertil. Steril, 47, (1987)

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