FERTILIZATION INVITRO OF SUPERNUMERARY OOCYTES FOLLOWING GAMETE INTRAFALLOPIAN TRANSFER (GIFT)

被引：2

作者：

CRITCHLOW, JD

MATSON, PL

TROUP, SA

IBRAHIM, ZHZ

BURSLEM, RW

BUCK, P

LIEBERMAN, BA

机构：

[1] Regional IVF Unit, St Mary's Hospital, Manchester M13 0JH, Whitworth Park

[2] Manchester Fertility Services Ltd, Manchester BUPA Hospital, Manchester M16 8AJ, Russell Road, Whalley Range

来源：

HUMAN REPRODUCTION | 1990年 / 5卷 / 07期

关键词：

GIFT; IVF; Supernumerary oocytes;

D O I：

10.1093/oxfordjournals.humrep.a137197

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Gamete intra-Fallopian transfer (GIFT) was performed in 130 treatment cycles over a 17-month period. In 91% (118/130) of the cycles one or more oocytes were available for insemination in vitro and only GIFT cycles with supernumerary oocytes were included in the present study. Pituitary and ovarian suppression was arhieved with buserelin followed by stimulation of multifollicular development by human menopausal gonadotrophin (HMG). Failure of supernumerary oocytes to fertilize was associated with a significantly reduced pregnancy rate (3/23; 13%) compared to cycles where fertilization occurred in vitro (35/95; 37%). These findings demonstrate that the outcome of IVF of supernumerary oocytes may be of particular diagnostic value in couples where the female partner has not conceived following treatment by GIFT after pituitary down-regulation with buserelin and ovarian stimulation with HMG. © 1990 Oxford University Press.

引用

页码：853 / 856

页数：4

共 27 条

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