STUDIES ON AMINO-ACID-SEQUENCES OF 2 ISOFORMS OF 17-KDA ESSENTIAL LIGHT CHAIN OF SMOOTH-MUSCLE MYOSIN FROM PORCINE AORTA MEDIA

被引：25

作者：

HASEGAWA, Y

UEDA, Y

WATANABE, M

MORITA, F

机构：

[1] Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo, Hokkaido 060, Kita-ku

来源：

JOURNAL OF BIOCHEMISTRY | 1992年 / 111卷 / 06期

关键词：

D O I：

10.1093/oxfordjournals.jbchem.a123839

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Amino acid sequences were analyzed for two isoforms of myosin essential light chain, LC17a and LC17b [Hasegawa, Y., Ueno, H., Horie, K., & Morita, F. (1988) J. Biochem. 103, 15-18] from porcine aorta smooth muscle. Both LC17a and LC17b consisted of 150 amino acid residues and their N-terminal Cys residues were blocked by an acetyl group. The amino acid sequences of LC17a and LC17b were common from the N-terminal to Glu-141 and five amino acid substitutions were observed within the remaining C-terminal 9 residues. The amino acid sequences of LC17a and LC17b were identical to those deduced from the nucleotide sequences of bovine aortic cDNAs encoding the two isoforms.

引用

页码：798 / 803

页数：6

共 24 条

[21] EXPRESSION OF SMOOTH-MUSCLE SPECIFIC ALPHA-ISOACTIN IN CULTURED VASCULAR SMOOTH-MUSCLE CELLS - RELATIONSHIP BETWEEN GROWTH AND CYTODIFFERENTIATION [J].