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CAN IMMOBILIZATION BE EXPLOITED TO MODIFY ENZYME-ACTIVITY

被引：119
作者：
CLARK, DS
机构：
[1] Department of Chemical Engineering, University of California, Berkeley
来源：
TRENDS IN BIOTECHNOLOGY | 1994年 / 12卷 / 11期
关键词：
D O I：
10.1016/0167-7799(94)90018-3
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Immobilization has long been recognized as a useful tool for retaining enzymes in bioreactors and enabling the continuous operation of enzymic processes. However, the potential of immobilization for modifying enzyme activity in an advantageous, if not predictable, manner is less-well appreciated. This review summarizes selected studies that have used immobilization to tailor the catalytic properties of enzymes, and highlights the application of immobilization to the rational design of biocatalysts.
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页码：439 / 443
页数：5
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