THE ROLE AND TREATMENT OF HELICOBACTER-PYLORI INFECTION IN PEPTIC-ULCER DISEASE - A REVIEW OF THE RELATIONSHIP BETWEEN HELICOBACTER-PYLORI INFECTION AND PEPTIC-ULCER DISEASE

被引:8
作者
FLETCHER, PJ
CRAIG, DQM
机构
[1] NORTHWICK PK HOSP & CLIN RES CTR,CHEM PHARMACOL UNIT,WATFORD RD,HARROW HA1 3UJ,MIDDX,ENGLAND
[2] UNIV LONDON,SCH PHARM,CTR MAT SCI,LONDON WC1N 1AX,ENGLAND
关键词
D O I
10.1111/j.1365-2710.1993.tb00595.x
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The role of Helicobacter pylori in the progress of peptic ulcer disease is reviewed. In Particular, the relationship between H. pylori infection and relapse rate is discussed, including an overview of current theories regarding the mechanism of tissue damage induced by the organism. The relative merits of the recommended drug therapies are outlined, with emphasis on their effectiveness in removing H. pylori from the gastrointestinal tract, the risks of the development of resistant strains of the organism, the adverse effects of the therapies and the approaches that are likely to be adopted in the future.
引用
收藏
页码:311 / 316
页数:6
相关论文
共 45 条
[41]  
TYTGAT GNJ, 1991, BRIT MED J, V302, P1535, DOI 10.1136/bmj.302.6791.1535-b
[42]   BISMUTH SUBSALICYLATE IN THE TREATMENT OF H2 BLOCKER RESISTANT DUODENAL-ULCERS - ROLE OF HELICOBACTER-PYLORI [J].
WAGNER, S ;
GEBEL, M ;
HARUMA, K ;
BAR, W ;
LANGE, P ;
FREISE, J ;
GLADZIWA, U ;
SCHMIDT, FW .
GUT, 1992, 33 (02) :179-183
[43]  
WARREN JR, 1983, LANCET, V1, P1273
[44]   HELICOBACTER-PYLORI AND METRONIDAZOLE RESISTANCE [J].
WEIL, J ;
BELL, GD ;
POWELL, K ;
JOBSON, R ;
TROWELL, JE ;
GANT, P ;
JONES, PH .
LANCET, 1990, 336 (8728) :1445-1445
[45]   RELAPSE OF DUODENAL-ULCER [J].
WORMSLEY, KG .
BRITISH MEDICAL JOURNAL, 1986, 293 (6560) :1501-1501