NERVE-FIBER CONDUCTION-VELOCITY DISTRIBUTIONS .2. ESTIMATION BASED ON 2 COMPOUND ACTION POTENTIALS

被引:83
作者
CUMMINS, KL
DORFMAN, LJ
PERKEL, DH
机构
[1] STANFORD UNIV,MED CTR,DEPT NEUROL,STANFORD,CA 94305
[2] STANFORD UNIV,DEPT BIOL SCI,STANFORD,CA 94305
来源
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY | 1979年 / 46卷 / 06期
关键词
D O I
10.1016/0013-4694(79)90102-0
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
A method is presented for estimating nerve fiber conduction velocity distributions from non-ivasive measurements of the compound action potential at two distinct locations separated by a known distance along the nerve bundle. This method is based on a model of the compound action potential as a weighted sum of delayed single-fiber action potential, but does not require explicit knowlege of the single-fiber action potential wave shapes in order to yield a unique estimate of the conduction velocity distribution. Illustrative examples are presented from normal and diseased nerves. This method appears to have clinical applications in the electrophysiological assessment of peripheral nerve function. © 1979.
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页码:647 / 658
页数:12
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