REDUCTIONS AND RADICAL CYCLIZATIONS OF ARYL AND ALKYL BROMIDES MEDIATED BY NABH4 IN AQUEOUS BASE

被引：68

作者：

RAI, R ^{[1
]}

COLLUM, DB ^{[1
]}

机构：

[1] CORNELL UNIV,BAKER LAB,DEPT CHEM,ITHACA,NY 14853

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 34期

关键词：

RADICAL CYCLIZATION; SODIUM BOROHYDRIDE; AQUEOUS;

D O I：

10.1016/S0040-4039(00)73396-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reductions and free radical cyclizations of alkyl- and aryl bromides are effected in aqueous base by NaBK4 in conjunction with a base-soluble dialkyltin(IV) reagent and 4,4'-azobis(4-cyanovaleric acid) (ACVA). The aryl bromides reduce at lower rates under tin-free conditions using simply NaBH4-ACVA.

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页码：6221 / 6224

页数：4

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