Can DNA polymerase I (Klenow fragment) serve as a model for other polymerases?

被引：34

作者：

Joyce, Catherine M. ^{[1
]}

机构：

[1] Yale Univ, Med Sch, Dept Mol Biophys & Biochem, 333 Cedar St, New Haven, CT 06510 USA

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1991年 / 1卷 / 01期

关键词：

D O I：

10.1016/0959-440X(91)90020-T

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent protein-sequence comparisons suggest that a small number of important active-site residues may be conserved between all polymerases, even those of different classes.

引用

页码：123 / 129

页数：7

共 34 条

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[18] THE HERPES-SIMPLEX VIRUS TYPE-1 DNA-POLYMERASE GENE - SITE OF PHOSPHONOACETIC ACID RESISTANCE MUTATION IN STRAIN ANGELOTTI IS HIGHLY CONSERVED
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[J]. JOURNAL OF GENERAL VIROLOGY, 1987, 68 : 1429 - 1433
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