METHANE AS THE PRODUCT OF REACTION OF METHYL-COENZYME-M WITH MONOVALENT NICKEL-COMPLEXES IN AQUEOUS-SOLUTIONS - A MODEL FOR THE IN-VIVO ACTIVITY OF COFACTOR F-430

被引：14

作者：

ZILBERMANN, I ^{[1
]}

GOLUB, G ^{[1
]}

COHEN, H ^{[1
]}

MEYERSTEIN, D ^{[1
]}

机构：

[1] BEN GURION UNIV NEGEV,DEPT CHEM,IL-84105 BEER SHEVA,ISRAEL

来源：

INORGANICA CHIMICA ACTA | 1994年 / 227卷 / 01期

关键词：

NICKEL COMPLEXES; MACROCYCLIC LIGAND COMPLEXES; ENZYME COMPLEXES;

D O I：

10.1016/0020-1693(94)04301-9

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Solutions containing the monovalent macrocyclic nickel complexes 1 and 2 were prepared by irradiating with ionizing radiation He saturated solutions containing the divalent complexes and 0.01 M HCO2Na. Deaerated solutions containing methyl-coenzyme-M (MeCoM) were then injected into the vials containing the monovalent complexes. Vague traces of methane were detected at pH 7.4 while at pH 9.4 the yield of methane is over 10%. Blank experiments point out that MeCoM scavenges methyl free radicals via a mechanism which does not produce methane as the major product. A mechanism for the formation of methane in these reactions is proposed.

引用

页码：1 / 3

页数：3

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