CYTOGENETICS OF A CASE OF ECCRINE SPIRADENOMA

被引：26

作者：

DIJKHUIZEN, T

VANDENBERG, E

NIKKELS, PGJ

HOEKSTRA, HJ

DEJONG, B

机构：

[1] UNIV GRONINGEN,DEPT MED GENET,ANTONIUS DEUSINGLAAN 4,9713 AW GRONINGEN,NETHERLANDS

[2] UNIV GRONINGEN,DEPT PATHOL,9713 AW GRONINGEN,NETHERLANDS

[3] UNIV HOSP GRONINGEN,DEPT SURG ONCOL,GRONINGEN,NETHERLANDS

来源：

HUMAN PATHOLOGY | 1992年 / 23卷 / 09期

关键词：

SWEAT GLAND NEOPLASM; ECCRINE SPIRADENOMA; CYTOGENETICS; MALIGNANT TRANSFORMATION;

D O I：

10.1016/0046-8177(92)90274-7

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

A cytogenetic study of an eccrine spiradenoma and two lymph node metastases, with a growth pattern and microscopic appearance typical for benign eccrine spiradenoma, revealed a 46,XY,-5,del(16)(q22),+mar(t(?;5)(?::5q13→5qter)) karyotype. The finding of the same abnormal karyotype in the tumor and the metastases suggests a relationship between the chromosomal abnormalities and the clinical malignant behavior of this morphologic benign tumor. © 1992.

引用

页码：1085 / 1087

页数：3

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