AJMALICINE METABOLISM IN CATHARANTHUS-ROSEUS CELL-CULTURES

被引：14

作者：

DOSSANTOS, RI

SCHRIPSEMA, J

VERPOORTE, R

机构：

[1] LEIDEN UNIV,LEIDEN AMSTERDAM CTR DRUG RES,DIV PHARMACOGNOSY,GORLAEUS LABS,2300 RA LEIDEN,NETHERLANDS

[2] UNIV FED RIO GRANDE SUL,FAC FARM,PORTO ALEGRE,BRAZIL

来源：

PHYTOCHEMISTRY | 1994年 / 35卷 / 03期

关键词：

CATHARANTHUS ROSEUS; APOCYNACEAE; PLANT CELL CULTURE; METABOLISM; TURNOVER; CATABOLISM; INDOLE ALKALOID; AJMALICINE;

D O I：

10.1016/S0031-9422(00)90585-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Ajmalicine degradation was investigated in a low alkaloid-accumulating Catharanthus roseus cell culture, and compared with the chemical degradation which occurred in medium without cells. Degradation was found to be faster in the presence of cells. By adding [Me-H-2(3)] ajmalicine to the cell culture the production and the degradation rates were estimated. Both were relatively high at the beginning of the growth phase while the degradation rate was also high in the stationary phase.

引用

页码：677 / 681

页数：5

共 20 条

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