SMALL RNA HELICES AS SUBSTRATES FOR AMINOACYLATION AND THEIR RELATIONSHIP TO CHARGING OF TRANSFER-RNAS

被引：41

作者：

FRANCKLYN, C

MUSIERFORSYTH, K

SCHIMMEL, P

机构：

[1] MIT, DEPT BIOL, CAMBRIDGE, MA 02139 USA

[2] UNIV VERMONT, COLL MED, DEPT BIOCHEM, BURLINGTON, VT 05405 USA

来源：

EUROPEAN JOURNAL OF BIOCHEMISTRY | 1992年 / 206卷 / 02期

关键词：

D O I：

10.1111/j.1432-1033.1992.tb16929.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

RNA microhelices that reconstruct the acceptor stems of transfer RNAs can be aminoacylated. The anticodon-independent aminoacylation is sequence-specific and suggests a relationship between amino acids and nucleotide sequences which is different from that of the classical genetic code. The specific aminoacylation of RNA microhelices also suggests a highly differentiated adaptation of the structures of aminoacyl-tRNA synthetases to sequences in the acceptor stems of transfer RNAs.

引用

收藏

页码：315 / 321

页数：7

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