INTRACEREBRAL GRAFTING OF CATECHOLAMINE PRODUCING CELLS AND RECONSTRUCTION OF DISTURBED BRAIN-FUNCTION

被引：18

作者：

NISHINO, H

机构：

[1] Department of Physiology, Nagoya City University Medical School, Mizuho-ku, Nagoya, 467, Mizuho-cho

来源：

NEUROSCIENCE RESEARCH | 1993年 / 16卷 / 03期

关键词：

NEURAL TRANSPLANTATION; CATECHOLAMINE; DOPAMINE; ADRENAL MEDULLA; SUBSTANTIA-NIGRA; IMMUNOLOGY; TROPHIC FACTOR; PARKINSONS DISEASE;

D O I：

10.1016/0168-0102(93)90120-F

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The objective of neural transplantation is to improve and reconstruct deteriorated brain function through an intracerebral implant of neural or paraneural tissues. In the last decade, basic research in this field has made great progress and brought magnificent results. Recently, the clinical application for treatment of Parkinson's disease has started and some fruitful effects are seen. Neural transplantation, on the other hand, is a useful tool in neurobiology to study the attention attracting themes, i.e., regeneration, development, plasticity, gene expression, neuroimmunology, trophic factor, etc. In this review, the functional recovery, mechanism, trophic factor, and clinical applications will be discussed pertaining to intracerebral grafting of catecholamine producing cells.

引用

页码：157 / 172

页数：16

共 158 条

[61] A THEORY OF THE FUNCTIONAL-ORGANIZATION OF THE NEOSTRIATUM AND THE NEOSTRIATAL CONTROL OF VOLUNTARY MOVEMENT [J].