SEQUENCE CHARACTERIZATION AND GENETIC-MAPPING OF THE HUMAN VSNL1 GENE, A HOMOLOG OF THE RAT VISININ-LIKE PEPTIDE RNVP1

In the course of isolation and sequence analysis of microsatellite repeat containing human cDNAs, we have isolated the human homologue of the rat visinin-like peptide gene. The human gene shows a high degree of conservation at both the amino acid and the DNA sequence level. The (CA)(n) microsatellite repeat embedded in the 3' untranslated region of the gene is conserved between rat and human, along with the flanking DNA sequences. We have mapped the VSNL1 gene to the short arm of chromosome 2. (C) 1995 Academic Press, Inc