AN SAR STUDY FOR THE NONPEPTIDE SUBSTANCE-P RECEPTOR (NK1) ANTAGONIST, CP-96,345

被引：19

作者：

HOWSON, W

HODGSON, J

RICHARDSON, R

WALTON, L

GUARD, S

WATLING, K

机构：

[1] Parke-Davis Neuroscience Research Centre, Addenbrookes Hospital Site, Cambridge, CB2 2QB, Hills Road

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1992年 / 2卷 / 06期

关键词：

D O I：

10.1016/S0960-894X(01)81197-5

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Results from an SAR study around the novel, non-peptide substance P receptor NK antagonist, (+/-)CP-96,345 (1) are described. The importance of the 2-degrees nitrogen and the aromatic moieties are clarified.

引用

页码：559 / 564

页数：6

共 18 条

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