CHARACTERIZATION OF THE ALTERNATIVE OXIDASE PROTEIN IN THE YEAST HANSENULA-ANOMALA

被引：44

作者：

SAKAJO, S

MINAGAWA, N

YOSHIMOTO, A

机构：

[1] Department of Biochemistry, Niigata College of Pharmacy, Niigata, 950-21

来源：

FEBS LETTERS | 1993年 / 318卷 / 03期

关键词：

CYANIDE-RESISTANT RESPIRATION; ALTERNATIVE OXIDASE; AMINO ACID SEQUENCE SIMILARITY; MITOCHONDRIA; HANSENULA-ANOMALA;

D O I：

10.1016/0014-5793(93)80535-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The cyanide-resistant respiratory pathway is induced by respiratory inhibitors in the yeast Hansenula anomala. A monoclonal antibody against the alternative oxidase in the higher plant Sauromatum guttatum cross-reacted with a 36-kDa mitochondrial protein induced by antimycin A in H. anomala and with a protein encoded by a cDNA which was previously cloned for an antimycin A-inducible mRNA in the yeast. There was a similarity in the amino acid sequence between the cDNA-encoded protein and the plant alternative oxidase protein. We propose that the 36-kDa mitochondrial protein encoded by the cDNA is a component of alternative oxidase in H. anomala.

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页码：310 / 312

页数：3

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